Takeaway
Transcranial magnetic stimulation (TMS) of the anterior cingulate cortex (ACC) and posterior superior insula (PSI) had no significant analgesic effect in people with central neuropathic pain (CNP) compared with sham-treated people, although there was a significant decrease in anxiety scores in the ACC-stimulated group and an increase in heat pain threshold in the PSI-stimulated group.
Why this matters
Despite not clinically significant, effects of stimulation of the ACC and PSI may provide insights into CNP which remains a significant burden on patients.