Brain regions associated with impaired verbal fluency in Parkinson’s disease

Takeaway

  • In those with Parkinson’s disease (PD), impaired semantic and phonemic fluency were associated with protein burden in the transentorhinal cortex and limbic regions, respectively.

Why this matters

  • The association of different regions of pathological burden with various facets of impaired verbal fluency indicates that tests of verbal fluency should not be interpreted interchangeably.