Takeaway
The Chronic Migraine Epidemiology and Outcomes (CaMEO) study identified that opioid use for migraine treatment is associated with a greater incidence of comorbidities and poorer quality-of-life compared with non-opioid treatment.
Why this matters
Some individuals with migraine administer opioids for acute treatment, although factors associated with the use of opioids for migraine are not well established.