Correlation of perimysial inflammatory infiltrates to myalgia and elevated creatine kinase levels

Takeaway

  • Muscle biopsy is unlikely to detect a specific pathology in patients with isolated myalgia, elevated creatine kinase, or both, unless the electromyography (EMG) shows alterations suggestive of myopathy.

Why this matters

  • Inflammatory infiltrates are found in muscle biopsies that do not conform to clinical or histologic criteria for diagnosis purposes.