Could neurosurgery reduce seizures in temporal lobe epilepsy?

Takeaway

  • Surgical removal of at least 50% of the piriform cortex increases the odds of patients with temporal lobe epilepsy becoming seizure-free 16-fold.

Why this matters

  • Improved understanding of the areas of the brain involved in the generation of seizures in patients with temporal lobe epilepsy will help guide the development of novel surgical and pharmacologic interventions.