Fibulin 2 is a possible candidate gene for increased risk of intracranial aneurysm

Takeaway

  • This study did not find support for any low-frequency genetic variants affecting intracranial aneurysm risk but did identify a potential candidate gene: fibulin 2 (FBLN2) encoding for a extracellular matrix protein playing a role in the formation of blood vessels lamina.

Why this matters

    This study identified a candidate gene for further study, which could impact future developments in understanding intracranial aneurysm risk.