Functional connectivity correlates of cognitive deficits in neuromyelitis optica spectrum disorder

Takeaway

  • Functional reorganization occurs in individuals with neuromyelitis optica spectrum disorder (NMOSD) at the level of cognitive networks with an overall adaptive role of increased resting state (RS) functional connectivity (FC).

Why this matters

  • Increased FC may attenuate the negative impact of NMOSD-related tissue damage and help patients maintain a normal cognitive function.