Inpatient seizure risk prediction score validated in new study

The 2HELPS2B score for inpatient seizure risk prediction has been validated in a study reported at AAN 2021.

Dr Mohammed Tabaeizadeh from Baylor College of Medicine and Massachusetts General Hospital, Boston, USA, said subclinical and electrographic seizures are relatively common (10-12%) in hospitalized patients. Electrographic seizures are associated with worse clinical outcomes, including an increased risk of future epilepsy.

The 2HELPS2B scoring system was developed to aid prediction and help inform the use of continuous electroencephalogram monitoring (cEEG). It takes into account factors including frequency above 2 Hz, independent sporadic epileptiform discharges, lateralized periodic discharges, lateralized rhythmic delta activity, bilateral independent periodic discharges, and prior seizures.