Investigating the association between C-reactive protein levels and risk of ischemic stroke

Takeaway

  • C-reactive protein (CRP)-associated single nucleotide polymorphisms (SNPs) are not causally associated with risk of ischemic stroke (IS).

Why this matters

  • It is uncertain whether CRP-associated inflammation underlying IS pathophysiology is a causal factor for this disease.

  • Understanding the causal factors for IS could enable development of new preventative therapies.