Meta-analysis of plasma creatinine as a prognostic biomarker for amyotrophic lateral sclerosis

Takeaway

  • Plasma creatinine shows promising results as a prognostic biomarker for amyotrophic lateral sclerosis (ALS); higher levels of creatinine are associated with increased survival and better functional scores.

Why this matters

  • Current ALS diagnosis is based upon clinical criteria that lack the precision to enable a rapid diagnosis; biomarker validation will therefore aid ALS patient diagnosis and prognosis.