Optical coherence tomography-angiography is a novel non-invasive biomarker for early Alzheimer’s disease

Takeaway

  • People with prodromal Alzheimer’s disease have marked changes in retinal perfusion parameters, measured by highly sensitive angiography, without altered retinal morpho-structural measures.

Why this matters

    People with Alzheimer's disease have reduced retinal thickness and altered retinal perfusion. These novel findings using new non-invasive imaging techniques, demonstrate the potential role of optical coherence tomography-angiography as non-invasive biomarkers for detection of early Alzheimer’s disease.