Optimal interictal localization of the epileptogenic zone is achieved in non-rapid eye movement sleep

Takeaway

  • Localization of the epileptogenic zone in interictal electroencephalography is best achieved during non-rapid eye movement sleep.

Why this matters

    Compared to traditional surrogates of the epileptogenic zone, which require several days of recording, the multi-feature approach achieved in 10 minutes could lead to more time-efficient intracranial presurgical investigation of focal epilepsy.